I am not a comic or cartoon fan, per se; but I do have a favorite of each. My favorite comic, of course, is Dilbert; I can totally relate to that guy when it comes to office politics (not when it comes to his personal life.)
My favorite cartoon is not even on TV. His name is Strong Bad, and the dude is absolutely hilarious to me!! I'm not going to try to explain to you who is and why he has the name of Strong Bad - it is a very painful process; I'll just say that either you'll get him or you won't (like my wife!) Anyway, the storyline is that he answers real e-mails from people (sometimes even outside the country), usually accompanied by some mischief! I usually check in about every other month or so, and I noticed that he is celebrating e-mail #200.
You da man, SB!